Who we are and what we offer
genetics > computing > nutrient formulations
VHL harnesses multi-omics data, AI and informatics to create bio-matched nutrients to optimize cellular performance. specialize in micro-environment engineering, basal media formulations, supplements and feeds, bioreactor additives, transitioning to chemically defined culture (cell lines and microbes), transfection reagents (coming soon), and pluronic replacements (coming soon).
Basal media formulation
Expression feed formulation
Growth feed formulation
Chemically-defined transition: Ser-X
Matching nutrient substrates to metabolic and genetic 'fingerprints'.
The technology is applicable to any cell, tissue, or organism type, and culture/bio-manufacturing setting. The platform can also be customized to optimize key metrics of interest (growth/cell proliferation, viability, protein production/titer, etc.). Our partners span biologics production, precision fermentation, tissue culture, and precision medicine. Ask to see our supporting data for cell proliferation and gene-expression/protein production across mammalian cells and microbes. We regularly achieve multiple fold changes in titer for both cell density and protein production and reduce costs by 70-90%.
In addition, we teach our partners how to formulate and optimize in order to eliminate supplier dependence and enable greater scaling and profitability.
Enable
Facilitate a broad range of complex biologics and innovative research
1
Increase feasibility
Increase the probability of successfully developing cell-based products
2
Accelerate
Accelerate product dev/R&D cycle
3
Increase your bottom line
Drastically improve process yield and lower costs throughout the value chain
4
Increase ROI
Increase ROI for cell-based products
5
Stake new IP
Our formulations/platform can be harnessed as novel bio-manufacturing IP around your cell-based product
6
End-to-end optimization
By optimizing the metabolism of your cells, you optimize your bottom line, I.e. 40-900% greater yield just by changing your media or feed.
Only scalable solution
Our solutions are fully scalable and regulatory friendly, as VHL provides formulations and recommendations in lieu of physical products.
Precision nutrition as a service
We also regularly work with partners who need precision micro-environments for high-fidelity research/therapeutics testing.
Our innovative solutions extend beyond our bio-platform
Auxiliary Products/Complementary Technologies:
1. Growth additives for microbes and cell lines.
2. Expression additives for microbes and cell lines.
3. Organic pluronic replacement for cell lines.
Coming soon: The world’s first mammalian transfection reagent that’s affordable and actually good for your cells.
**We’re working hard to add new offerings to this list! Get in touch to hear more about what we have in development.**