THE VHL PLATFORM

Cells are the foundation of all life, producing essential products such as therapeutics, food, and fuel.

However, our current formulations for culturing and harnessing these cells relies on trial and error to find the best formulations.

We start by giving the cell exactly what it needs.

Our platform streamlines this process and optimizes a cell’s capabilities by reducing unnecessary metabolic steps. By
giving the cell exactly what it needs from the start, we increase growth and production, lower bio-manufacturing costs,
and maximize effciency.

How do we do it?

Each cell has specific genetic data that we can analyze to tell us what the cell needs to perform optimally. Bioinformatics and chemistry allow us to find the best formula for the individual cell type in question. After finding the optimal nutrient formula, the cell’s productivity is no longer inhibited by unneeded metabolic steps, which increases the robustness of the bio-process at the molecular level.

Cells' genetic data has never been used like this before.

We harness genetic data in new way, with a type of analysis that allows us to optimize a cell’s metabolism by designing the most efficient inputs to match the cell’s needs. Our technology takes the guess-work out of media design.

We work in conjunction with you to assess bottlenecks in your process and gather omics data either directly from your cells or from public databases.

We then couple our proprietary bioinformatics platform with in-house analysis to determine the optimal components and concentration for the unique metabolism of the cells.

The formula is then tested for quality and optimized.

Working together, we then assess the most mutually beneficial way to protect, produce, and commercialize your formula.

THE PLAN

Our goal is to extend use of the platform to improve applications that enhance the health of humans and the planet.

Van Heron Labs uses genetic analysis and biocomputing to determine the specific nutrient substrates that biosystems need for optimal function. For companies harnessing organisms or cells, VHL can computationally perfect cellular environments to increase yields, decrease both costs and R&D timelines, and enable scale-up. Our platform has seen success with several cell types and applications, including precision fermentation, mammalian cell culture, and cellular agriculture.

Cellular Agriculture

Biologics

Cell Therapy

Gene Therapy

Precision Fermentation

Stem cell applications

Cellular Agriculture

Biologics

Cell Therapy

Gene Therapy

Precision Fermentation

Stem cell applications

Reprogramming Metabolism Without Genetic Engineering....
Reprogramming Metabolism Without Genetic Engineering....
THE PERFORMANCE

Bacterial and Mammalian Cells

In mammalian cells, our technology has achieved many fold changes in growth and up to 70% reductions in cost. In microbial cells, our technology has achieved up to 90% increases in growth and many fold changes in specific gene expression/protein production, saving considerable bio-production cost. These optimizations in cell growth and specific production occur simultaneously providing evidence of beneficial metabolic reprogramming.

Mammalian Performance

310% increases in cell density - 900% with adjuvant and additional oxygen

Mammalian Cell Media

> 70% reductions in growth media cost

Protein Production

360% increases in specific productivity for bacteria

To see our data deck please send a message to:
[email protected]

Let us ‘biohack’ your system to unlock greater potential.

Our technology relies only on your cell's natural metabolism and the power of biocomputing to create healthier, higher producing, and higher yielding organic systems